Education & Background

2010 - 2015 Postdoctoral Fellow Harvard University / Wyss Institute for Biologically Inspired Engineering, Boston, MA
2010 Ph.D. in Chemistry Tufts University / Department of Chemistry Medford, MA
2003 B.Sc. in Chemistry Bogazici University / Department of Chemistry Istanbul / Turkey

Research Focus

Protein design and engineering.

Publications

1. Yüksel, D.; Bianco, P.R.; Kumar, K. “De novo Design of Protein Mimics of B-DNA” Mol. Biosyst. 2016, 12, 169-177.
2. Yüksel, D.; Nguyen, P.Q.; Ingber, D.E. “Peptides for Targeting Therapeutics and Diagnostics to Early and Late Stage Breast Cancer Lesions” US Provisional Patent Application (pending), filed Jan 26, 2015.
3. Bischof, A.G.; Yüksel, D.; Mammoto, T.; Mammoto, A.; Ingber, D.E. “Tumor Normalization Induced by Embryonic Extracellular Matrix” Integr. Biol. 2013, 5, 1045-1056.
4. Gee, E.P.S.; Yüksel, D.; Stultz, C.M.; Ingber, D.E. “SLLISWD Sequence in the 10FNIII Domain Initiates Fibronectin Fibrillogenesis” J. Biol. Chem. 2013, 288, 21329-21340.
5. Gee, E.P.S.; Yüksel Yurt, D.; Stultz, C.M.; Ingber, D.E. “Designing Novel Peptides for Inducing Fibronectin Matrix Assembly” PCT/US13/31193 filed March 14, 2013.
6. Wälchli, T.; Pernet, V.; Weinmann, O.; Shiu, J.; Guzik-Kornacka, A.; Decrey, G.; Yüksel, D.; Schneider, H. Vogel, J.; Ingber, D.E.; Vogel, V.; Frei, K.; Schwab, M.E. “Nogo-A is a Negative Regulator of CNS Angiogenesis” Proc. Natl. Acad. Sci. USA 2013, 110, E1943-E1952.
7. Lorenz, B.; Álvarez de Cienfuegos, L.; Oelkers, M.; Kriemen, E.; Brand, C.; Stephan, M.; Sunnick, E.; Yüksel, D.; Kalsani, V.; Kumar, K.; Werz, D.; Janshoff, A. “A Model System for Cell Adhesion Mediated by Weak Carbohydrate-Carbohydrate Interactions” J. Am. Chem. Soc. 2012, 134, 3326-3329.
8. Yüksel, D.; Pamuk, D.; Ivanova, Y.; Kumar, K. “Protein Engineering Using Noncanonical Amino Acids” in Protein Engineering and Design Park, S. and Cochran, J. Eds., Taylor & Francis 2009, invited chapter, pp 205-222.
9. Torres, O.; Yüksel, D.; Bernardina, M.; Kumar, K.; Bong, D. “Peptide Tertiary Structure Nucleation by Sidechain Crosslinking with Metal Complexation and Double Click Cycloaddition” ChemBioChem 2008, 9, 1701-1705.
10. Yoder, N.C.; Yüksel, D.; Dafik, L.; Kumar, K. “Bioorthogonal Noncovalent Chemistry: Fluorous Phases in Chemical Biology” Curr. Opin. Chem. Biol. 2006, 10, 576-583.